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Inhibiting NF-κB improves heart function in a mouse model of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a devastating genetic disease that impairs cardiac and skeletal muscle development. People with DMD gradually lose ambulation in childhood, acquire respiratory and heart failure in young adulthood and succumb to the disease by their mid-thirties. Until recently, there has been no effective treatment for the characteristic muscle-wasting progression of this disease. Provisional FDA approval of the first DMD therapy (eteplirsen) and improved disease management strategies have extended the life span of DMD patients and expanded the field of DMD research into later-stage outcomes such as cardiomyopathy (heart failure).
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Hope for Gabe (H4G)Hope for Gabe Foundation was created in ...
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Relationship of Right Ventricular Size and Function with Respiratory Status in Duchenne Muscular DystrophyThe relationship between pulmonary funct...
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The Gene-Edited Babies And CRISPR-Cas9 Controversy, ExplainedOutrage continues to grow over the news ...
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Experts review current and potential treatments for Duchenne muscular dystrophyExperts provided an overview of the many...
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Tadalafil and Sildenafil for Duchenne Muscular DystrophyThis study, supported by Parent Project ...
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Antisense Therapeutics to commence muscular dystrophy trialsAntisense Therapeutics is planning to un...
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Phase IIb Study of PRO045 in Subjects With Duchenne Muscular DystrophyThe purpose of the study is to see wheth...