Muscular dystrophy clue | DuchenneXchange

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Muscular dystrophy clue


Patients with Duchenne muscular dystrophy (DMD) have a genetic mutation that causes incurable muscle degeneration. Research has shown that the immune system plays a complex, double-sided role in muscular dystrophy — promoting both muscle repair and muscle degradation.

In their recent article in Frontiers in Pharmacology, Jonathan H. Soslow, MD, MSCI, Sergey Ryzhov, MD, PhD, and colleagues studied blood samples from normal people and people with DMD, and found that the patients with DMD had more T cells expressing a surface protein called CD26 compared to normal patients.

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