SGT-001 improves muscle function of dogs with Duchenne muscular dystrophy, studies show | DuchenneXchange

welcome to DuchenneXchange

- a positively charged Duchenne muscular dystrophy community.
  • join today!

SGT-001 improves muscle function of dogs with Duchenne muscular dystrophy, studies show


Solid Biosciences’ SGT-001 improved muscle activity in dogs with Duchenne muscular dystrophy (DMD), according to research the company presented at a Washington conference.

Another finding of the two preclinical-trial studies was that SGT-001 increased the expression of microdystrophin, a form of the protein dystrophin found in muscle. Too little of the protein is a hallmark of muscular dystrophy.

SGT-001 combats muscular dystrophy without disturbing the immune system or causing safety concerns, the studies also indicated.

https://www.duchennexchange.org/wp-content/uploads/2017/07/musculardystrophy.jpg