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Researchers

Hansell H. Stedman, MD

Researcher
Director
Muscular Dystrophy Research Institute for Human Gene Therapy
School of Medicine
University of Pennsylvania
Room 608 BRB II/III
421 Curie Blvd.
Philadelphia, Pennsylvania, United States

Dr. Hansell H. Stedman is currently working as Associate Professor of surgery at Perelman School of Medicine, University of Pennsylvania. He is also associated with Institute for Human Gene Therapy, University of Pennsylvania School of Medicine as Director of muscular dystrophy research.

Dr. Stedman is attending surgeon at hospital of the University of Pennsylvania as well as Veteran Affairs Medical Center, Philadelphia. He is also a member of The Institute for Translational Medicine and Therapeutics (ITMAT) where his studies pertain to genetics and disease mechanisms in Duchenne and limb-girdle muscular dystrophies.

Dr. Stedman’s research expertise lies in genetics & comparative genomics of contractile proteins, integrative biology of skeletal & cardiac muscle, pathobiology & therapy of muscular dystrophy & cardiomyopathy and vascular approaches to systemic gene delivery.

 

Representative Publications:

Mechanism of Deletion Removing All Dystrophin Exons in a Canine Model for DMD Implicates Concerted Evolution of X Chromosome Pseudogenes

Suite of clinically relevant functional assays to address therapeutic efficacy and disease mechanism in the dystrophic mdx mouse

Diaphragm remodeling and compensatory respiratory mechanics in a canine model of Duchenne muscular dystrophy

Inspiratory loading does not accelerate dystrophy in mdx mouse diaphragm: implications for regenerative therapy

Molecular approaches to therapy for Duchenne and limb-girdle muscular dystrophy

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