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Healthcare Providers

Katherine Mathews, MD

Healthcare Provider
Director
Iowa Neuromuscular Program
University of Iowa Health Care
1317 BT
200 Hawkins Drive
Iowa City, Iowa, United States

Dr. Mathews is interested in all aspects of Clinical Pediatric Neurology. Her particular interests include neuromuscular disorders and the neuropsychological outcome of childhood stroke. Her research career began with using genetic linkage, then a putative mouse model, to identify the gene causing facioscapulohumeral dystrophy. She has maintained an active interest in the impact of molecular genetics on neuromuscular diseases (diagnosis, pathophysiology, and treatment). She has served on NIH and CDC working groups to define the direction of research on neuromuscular disease in the future.

Dr. Mathews has become increasingly involved in collaborative clinical research efforts, many of which are laying a groundwork for clinical trials. She is currently a co-PI (with Paul Romitti, PhD) on the Iowa MDSTARnet project, a CDC sponsored, multi-center Duchenne/Becker Muscular Dystrophy surveillance and epidemiology project. She is a co-PI on one project of the University of Iowa’s NIH funded Wellstone Center, directed by Kevin Campbell, PhD and Steve Moore, MD, PhD. The project involves defining the phenotypes of patients with FRKP mutations and will extend nationwide. This clinical project was a key component of this successful NIH application. She is also the Iowa PI in the United Dystrophinopathy project; a genotype-phenotype study headed by Dr. Kevin Flanigan at the University of Utah and recently funded by the NIH.  

 

Representative Publications:

Perceived quality of life among caregivers of children with a childhood-onset dystrophinopathy: a double ABCX model of caregiver stressors and perceived resources

Prevalence of Duchenne and Becker muscular dystrophies in the United States

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