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Researchers

Lisa Maves, PhD

Researcher
Assistant Professor
Department of Pediatrics
University of Washington
4800 Sand Point Way
Seattle, Washington, United States

Dr. Lisa Maves is a principal investigator at Seattle Children’s Research Institute and an assistant professor of Pediatrics at the University of Washington School of Medicine. She received her PhD from the University of Washington and completed postdoctoral research at the University of Oregon and at Fred Hutchinson Cancer Research Center. She was a staff scientist at Fred Hutch before joining Seattle Children’s Research Institute in 2012.

Led by Dr. Lisa Maves, The Maves lab, investigates skeletal muscle and heart development, with the goal of making discoveries that lead to new treatments for muscular dystrophy and heart disorders. The lab uses the zebrafish as an animal model because of its advantages for genetic manipulations, in vivo imaging and drug screening. The goal of the lab is to establish zebrafish as a preclinical translation model for evaluating new drug therapies for Duchenne muscular dystrophy (DMD).

Her research focus areas include congenital heart defects, muscular dystrophy, and developmental biology.

 

Representative Publications:

Skeletal muscle fiber type: using insights from muscle developmental biology to dissect targets for susceptibility and resistance to muscle disease

Recent advances using zebrafish animal models for muscle disease drug discovery

Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat in a transgenic mouse model for FSHD

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