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Pier Lorenzo Puri, MD, PhD

Neuroscience and Aging Research Center
Sanford Burnham Prebys Medical Discovery Institute
10901 North Torrey Pines Road
La Jolla, California, United States

Pier Lorenzo Puri earned his M.D. at the University of Rome “la Sapienza” in 1991. Dr. Puri completed his internship in Internal Medicine at the hospital “Policlinico Umberto I” (Rome) and earned his Ph.D. at the University of Rome “la Sapienza”. During this time he was frequently working at the Freien University of Berlin, as visiting scientist. Since 2008, Dr. Puri is Adjunct Professor of Pediatrics at the University of California, San Diego and Associate Member of Sanford Children’s Health Research Center (Muscle Development and Regeneration program).

Dr. Puri’s lab investigates the mechanisms that control the reprogramming of cells and focuses on molecular pathways influencing gene expression particularly in muscle cells. His work helps to provide a better understanding of muscle regeneration in Duchenne. Dr. Puri has a lab in both San Diego as well as in Italy. The two labs work closely together and share data and resources.

Dr. Puri is also a member of the CureDuchenne Scientific Advisory Board.


Representative Publications:

Histological effects of givinostat in boys with Duchenne muscular dystrophy

Preclinical studies in the mdx mouse model of duchenne muscular dystrophy with the histone deacetylase inhibitor givinostat

Nitric oxide deficiency determines global chromatin changes in Duchenne muscular dystrophy