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Researchers

Yung-Yao Lin, PhD

Researcher
Blizard Institute
Barts and The London School of Medicine and Dentistry
The Blizard Building
4 Newark Street
London, United Kingdom

Dr Lin made significant contributions in the field of neuromuscular disorders, particularly towards the demonstration of novel genes responsible for muscular dystrophies using zebrafish models. In 2012, Dr Lin was awarded an Early Career Research fellowship from Barts and The London School of Medicine and Dentistry to set up his independent research group. He joined the Blizard Institute as a Lecturer in January 2013.

His researches mainly focus on the molecular and cellular mechanisms underlying muscular dystrophies. His research team is interested in developing cellular models for muscular dystrophies using the reprogramming and genome editing technologies to generate patient-specific induced pluripotent stem cell (iPSC) and isogenic control cells.

Representative Publications:

The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition

Mutations in GDP-mannose pyrophosphorylase B cause congenital and limb-girdle muscular dystrophies associated with hypoglycosylation of α-dystroglycan

Mutations in B3GALNT2 cause congenital muscular dystrophy and hypoglycosylation of α-dystroglycan

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