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Academic & Health Care Centers

Dubowitz Neuromuscular Centre

UCL Great Ormond Street Institute of Child Health
30 Guilford Street
London, United Kingdom
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The Dubowitz Neuromuscular Centre (DNC) provides a multidisciplinary service as a leading clinical and research centre specialising in neuromuscular disorders affecting individuals in the paediatric age. The DNC provides clinical assessment, diagnostic services, advice on treatment and rehabilitation, and is involved in clinical trials and in basic research focused on understanding the cause of neuromuscular diseases in childhood, and identifying novel therapeutic intervention.

The DNC is also a part of the Great Ormond Street NHS Trust and is a member of the MRC Neuromuscular Translational Research Centre at University College London. In addition to the service provided for all paediatric neuromuscular disorders, the DNC is involved with clinical, molecular, and cell biological research mostly focused on the genetic basis of congenital muscular dystrophies, on muscle stem cell, cell fusion, and on experimental therapies for Duchenne muscular dystrophy. The Muscle biopsy service is located close by at the Institute of Neurology at Queen Square. A dedicated team with expertise in paediatric muscle conditions works closely with adult muscle and nerve pathology service.