Cardiac Magnetic Resonance in Children With Muscular Dystrophy | DuchenneXchange

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Cardiac Magnetic Resonance in Children With Muscular Dystrophy

key information

study id #: NCT01081080

condition: Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Limb Girdle Muscular Dystrophy

status: completed

purpose:

This protocol will exploit novel state of the art cardiovascular magnetic resonance techniques to examine important changes in the heart in children with muscular dystrophy. The purpose of this study is to compare cardiac magnetic resonance (CMR) with the collected cardiac outcome data obtained in protocol: PITT1109 – Cardiac Outcome Measures in Children with Muscular Dystrophy.

mechanism of action: No pharmaceutical intervention

results: https://clinicaltrials.gov/ct2/show/results/NCT01081080

study details

start date: April 2010

estimated completion: October 2011

size / enrollment: 20

inclusion criteria:
Participant enrolled in the CINRG study: PITT1109 - Cardiac Outcome Measures in Children with Muscular Dystrophy

exclusion criteria:
• Pregnant woman (when uncertain, participants will undergo urine testing) or lactating women
• Decompensated congestive heart failure (unable to lie flat during CMR)
• Impaired renal excretory function (calculated Glomerular Filtration Rate less than 30mL/min)
• Contra-indications to Magnetic Resonance Imaging:
-Cardiac pacemaker or implantable defibrillator
-Cerebral aneurysm clip
-Neural stimulator
-Metallic ocular foreign body
-Harrington-rod
-Any implanted device (i.e. insulin pump, drug infusion device)
-Claustrophobia
-Metal shrapnel or bullet

study contacts

sponsor: Cooperative International Neuromuscular Research Group

investigators: Paula R Clemens, MD

locations: United States