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The Evaluation of Muscle Activation in Climbing up Stairs Activity in Children With Duchenne Muscular Dystrophy
study id #: NCT04287582
condition: Duchenne Muscular Dystrophy
Children with Duchenne Muscular Dystrophy (DMD) have difficulties towards the end of the ambulatory period, especially in activities that require lower extremity proximal muscle strength such as walking, climbing stairs, standing up without sitting. Stair climbing / descending activity is a complex activity that requires joint stability, correct muscle synergy and timing. When the literature is examined; It has been observed that the performance of stair climb up and down activity in individuals with neuromuscular disease has been evaluated with various clinical applications. In recent studies, there are surface electromyography (EMG) studies evaluating various aspects of stair climbing and descending activity.
Surface EMG; is a technique for neuromuscular evaluations that is frequently used in both research and clinical applications, noninvasive, and can be used in areas such as neurophysiology, sports science and rehabilitation.
Our study was planned to examine the muscle activations in the lower limb muscles involved in climbing up stairs activity in children with DMD and to compare healthy children with children with DMD and children with different levels of DMD.
Hypothesis originating from the investigation:
H0: There is no difference in the muscle activations measured by surface electromyography (EMG) of the involved lower extremity muscles during climbing up stairs activity between level 1 and level 2-3 children with early DMD.
H1: There is a difference in the muscle activations measured by surface electromyography (EMG) of the involved lower extremity muscles during climbing up stairs activity between level 1 and level 2-3 children with early DMD.
H2: There is no difference in the muscle activations measured by surface electromyography (EMG) of the involved lower extremity muscles during climbing up stairs activity between children with DMD and healthy children.
H3: There is a difference in the muscle activations measured by surface electromyography (EMG) of the involved lower extremity muscles during climbing up stairs activity between children with DMD and healthy children.
intervention: Electromyographic Device
mechanism of action: No pharmaceutical intervention
last updated: March 12, 2020
start date: April 3, 2019
estimated completion: March 7, 2020
phase of development: N/A
size / enrollment: 30
In our study, children will be assessed using the surface Electromyography (EMG) device by using electrodes placed in the relevant lower limb muscles that take part during the stair climbing activity.
The study included 10 children with DMD levels were 1 and 10 children with DMD levels were 2-3 according to the Brooke Lower Limb Functional Classification scale and 10 healthy children.
Muscle activation of vastus lateralis, biceps femoris, tibialis anterior and gastrocnemius medialis muscles will be measured by superficial electromyographic measurement. Muscle activation according to SENIAM (surface EMG for a non-invasive assessment of muscles) for will be evaluated.
Stair climbing activity will be performed 3 times and at 1 minute intervals.
- Surface Electromyographic Measurement [ Time Frame: 40 minutes ]
Muscle Activation Measurement It is an 8-channel system for measuring signals come from muscles (Delsys)
- Muscle Strength Measurement [ Time Frame: 15 minutes ]
A quantitative and objective method for assessment of muscular strength using a portable hand held dynamometer. Muscle strength measurement included lower limb and trunk muscles.
- Timed Performance Test [ Time Frame: 20 minutes ]
Timed function tests included time taken to stand from a supine position, time taken to walk 10 m, time taken to climb 4 standard-sized stairs and time taken to descend 4 standard-sized stairs.
- Muscle shortness assessment [ Time Frame: 10 minutes ]
Shortening assessment of trunk and lower extremity muscles measurement included back extensors, hamstring, hip flexors, quadriceps and gastrocnemius muscles.
- Six minute walk test [ Time Frame: 6 minutes ]
Children were asked to walk during 6 minutes as fast as possible at a 25 meter corridor.
• Eligible Sexes: male
• Having been diagnosed with Duchenne Muscular Dystrophy by a pediatric neurologist,
• Volunteering to participate in the study,
• Being in the 5-12 age range
• According to the Brooke Lower Limb Functional Classification developed for classifying lower extremity functions of children with DMD, it should be between level 1-3 (children who continue ambulation and can go up and down with assisted / unassisted stairs),
• To be able to cooperate with the instructions of the physiotherapist
• Not having a known acute or chronic illness
• The children with DMD included in the study have similar demographic characteristics (age, height, weight, body mass index),
• The physiotherapist should cooperate with the instructions.
Children with DMD:
• Have undergone any lower limb injuries and / or surgery,
• Started steroid treatment in the last 6 months,
• Having any systemic disease other than DMD,
• Not having permission from his family and himself.
• Having had any injury and / or surgery,
• Children with DMD have relatives,
• Not having permission from his family and himself
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