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Regression of Hamstring Flexibility and Performance in Children With Duchenne Muscular Dystrophy

key information

study id #: NCT03589612

condition: Duchenne Muscular Dystrophy, Performance, Flexibility

status: completed


Investigator investigated that regression of hamstring flexibility and performance in children with Duchenne Muscular Dystrophy.

mechanism of action: No pharmaceutical intervention

results: https://clinicaltrials.gov/ct2/show/results/NCT03589612

last updated: October 05, 2019

study details

start date: March 8, 2018

estimated completion: January 24, 2019

phase of development: N/A

size / enrollment: 60

study description:
Flexibility of hamstrings was evaluated by Popliteal Angle test. Performance was evaluated 6 Minute Walk Test (6 MWT). Regression of hamstring flexibility and performance was examined regression tests. Correlation was examined between popliteal angle test and parameter of North Star Ambulation Assessment.

primary outcomes:

  • Popliteal Angle Test [ Time Frame: 5 minute ]
    The Popliteal Angle Test was used to assess hamstring flexibility. Child asked to rise lower leg straight. Incomplete angle degree of full extension is popliteal angle.

secondary outcomes:

  • 6 Minute Walk Test [ Time Frame: 6 minute ]
    6 Minute Walk Test was used to assess performance with children Duchenne MUscular Dystropy.
  • North Star Ambulation Assessment [ Time Frame: 20 minute ]
    The North Star Ambulatory Assessment (NSAA) is used to assess mobility for in ambulatory children with DMD for 5 years. NSAA is consist of 17 items from stand to run.

inclusion criteria:

• Eligible Sexes:

• To be a Duchenne Muscular Dystrophy diagnosis,
• Being in the ambulatory period and climbing four steps independently,
• To be Level 1 and Level 2 according to Brooke Lower Functional Classification Test
• To be able to cooperate
• No any severe contracture in the lower limbs which may prevent assessments,

exclusion criteria:
• Children who fail to meet these criteria study.

study contacts

sponsor: Hacettepe University

investigators: Güllü Aydın Msc., Numan Bulut Msc, İpek Gürbüz Assoc.Prof., Ayşe Karaduman Prof.; Hacettepe University

trial center locations: Turkey