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Weekend Steroids and Exercise as Therapy for DMD
study id #: NCT04322357
condition: Duchenne Muscular Dystrophy (DMD)
status: not yet recruiting
purpose:The study team will determine the potential of low dose weekend prednisone and whether exercise training can synergize to delay disease progression and improve muscle strength/physical function in boys with Duchenne muscular dystrophy (DMD). Current standard of care (daily prednisone) is associated with adverse side effects. Evidence from DMD mouse models suggest that weekend dosing provides same efficacy without side effects. Appropriate exercise may also benefit but this area has not been adequately explored.
intervention: Drug: Prednisone, Behavioral: In-home Exercise Training
mechanism of action: Glucocorticoid to delay decline in muscle strength
results: https://clinicaltrials.gov/ct2/show/results/NCT04322357
last updated: September 22, 2020
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