Ward LM, Birnkrant DJ
In 2010, Bushby et al published the first-ever international comprehensive guidance on the diagnosis and management of patients with Duchenne muscular dystrophy (DMD) for practitioners. These recommendations were instrumental in raising awareness about the scope of the clinical care issues affecting boys and men with DMD and in initiating discussion around the world about the need to improve the quality and standardization of care. Almost a decade later, again in collaboration with the US Centers for Disease Control and Prevention, these documents have been updated to reflect the current approaches to the diagnosis and management of DMD, with key principles divided into the following 3 main articles:
Part I: diagnosis, neuromuscular care, rehabilitation, and endocrine (growth, puberty, obesity, and adrenal suppression) and nutritional management;
Part II: respiratory, cardiac, osteoporosis, and orthopedic management; and
Part III: primary, psychosocial, and emergency care and transitions of care across the lifespan.
For a multidisciplinary overview of assessments and interventions covering all topics and organized by stage of disease, see Fig 1, which is reproduced from the 2018 DMD Care Considerations published in The Lancet Neurology.
University of Ottawa and Children's Hospital of Eastern Ontario, Canada; Case Western Reserve University, USA
10.1542/peds.2018-0333B read more