source: Cell Therapy - Molecular and Translational Medicine
Meregalli M., Belicchi M., Torrente Y.
Here, we will describe the therapeutic potential of stem cell in the treatment of Duchenne muscular dystrophy (DMD). Moreover, we will examine pros and cons in the use of stem cells in clinical trials and the set of problems linked to the fine-tuning of protocols finalized to the generation of large numbers of transplantable cells. We will describe the experimental studies focused on the analysis of survival and functional efficacy of the grafted cells and the possible onset of adverse effects, such as immune rejection and tumor formation.
Università degli Studi di Milano, Italy